IN VIVO TEST
Bioavailibility test
To give you an earlier and more significant indicator of bioavailability than in vitro studies, ADME BIOANALYSES conducts an in vivo bioavailability test.
It consists in evaluating, during screening phase, the bioavailability of your compounds in order to have supplementary criteria of leads selection.
Indeed, 40% of the molecules are stopped in development phase due to a low level of bioavailability.
ADME BIOANALYSES developed this low cost test in order to enable you to know bioavailibility and pk indication of your compound within 1 month.
Blood Brain Barrier permeability test
Based on the same protocol, we can study the blood brain barrier permeability.
Homogenised brains are analysed with the same method. Ratios between plasma concentration and brain concentration are studied.
MICROSOMAL STABILITY
This test allows you to study the stability of your compound in presence of microsomes by measuring the level of the unchanged molecule.